血清降钙素原与C反应蛋白对感染性疾病的诊断价值

摘要

目的:探讨血清降钙素原(PCT)与c反应蛋白(CRP)对感染性疾病的诊断价值.方法:回顾性分析我院2012年1月至2012年8月间102例确诊为感染性疾病的患者的临床资料,探讨164例患者血清降钙素原及C反应蛋白的水平及其与感染性疾病之间的联系.以上病例均经我院实验室病原学检查及血清学检查等临床实验确诊.结果:血清降钙素原和C反应蛋白与感染的严重程度相关,感染源及疾病程度不同时,血清降钙素原及C反应蛋白水平不同.细菌性感染组与正常对照组的降钙素原相比差异有统计学意义(P＜0.05)；细菌感染组与病毒感染组降钙素原相比较时,差异有统计学意义(P＜0.05)；病毒感染组与正常对照组降钙素原比较无统计学差异(P＞0.05).三组之间的C反应蛋白相比,均有统计学差异(P＜0.05).结论:利用血清降钙素原和C反应蛋白的检测对临床感染进行诊断,可以提高感染性疾病诊断的准确率,且可根据实验结果判断感染性疾病的严重程度,值得临床推广.%Objective:To investigate the serum procalcitonin (PCT) and C-reactive protein (CRP) in the diagnosis of infectious diseases.Method:A retrospective analysis was designed to explore the relationship of procalcitonin and C-reactive protein levels and Infectious disease.All the cases were confirmed by clinical trials of pathogenic examination in our hospital clinical laboratory.Result:The level of procalcitonin and C-reactive protein in serum is related to the severity of the infection disease.The concentration of procalcitonin between bacterial infection group and normal control group was different statistically significant (P ＜0.05) ; the concentration of procalcitonin in the bacterial infection group compared to the original with the viral infection group,the difference was statistically significant (P ＜0.05) ; the concentration of procalcitonin in the infection group and normal control group was no significant difference (P＞ 0.05).C-reactive protein compared among the three groups,were statistically significant (P ＜0.05).Conclusion:Using the serum procalcitonin and C-reactive protein in the detection of clinical infection diagnosis can improve thc accuracy of the diagnosis in the infectious diseases.