Objective: To observe the diagnosis and treatment of critical limb ischemia, to provid basis for the improvement of clinical diagnosis rate and treatment effect. Method: The clinical data of 100 patients with critical limb ischemia treated in our hospital from August 2004 to August 2012 were analyzed and summarized. Result: As for perioperation period, the mortality rate was 4. 88% , the follow-up rate was 88.rn89%. The follow-up was 3-73 months, with average(18 ± 8 ) months, and the mortality rate during the follow-up period was 13. 01%. 1-3 years after operation, the patency rate was respectively ( 81±4 )% , ( 68± 6 )% and ( 61 ±7 )% . There were 25 patients with artery occlusion, 4 patients with two operation, and 9 patients with amputation. As for ulcer or necrotic wounds, the healing rate was 78. 85% half a year after operation , and the healing rate was 83. 65 % 1 year after operation. The limb salvage rate of 1 -3 years after operation was respectively ( 81±4 )% , ( 71±5 )% and ( 65±6 )%. Conclusion: Revascularization therapy of the combination of interventional technique, surgical bypass operation and stem cell transplantation to treat patients with critical limb ischemia can reduce the occurrence of complications, make vascular patency, reduce the amputation plane, speed up the healing of wound and improve the limb salvage rate. The treatment effect is significant.%目的:探讨重症下肢动脉缺血的诊断和治疗方法,为临床诊断率以及治疗效果的提高提供依据.方法:选取我院2004年8月至2012年8月收治的100例诊断为重症下肢动脉缺血患者的临床资料,进行分析和总结.结果:围手术期死亡率4.88%,随访率88.89%,进行为期3-73个月的随访,平均(18±8)个月,随访期间死亡率13.01%.术后1-3年通畅率分别为(81±4)%、(68±6)%、(61±7)%.动脉闭塞25例,二次手术4例,截肢9例.溃疡或坏死创面术后半年愈合率78.85%,1年愈合率83.65%.术后l-3年保肢率分别为(81±4)%、(71±5)%、(65±6)%.结论:重症下肢动脉缺血患者通过联合腔内介入技术、外科旁路手术及干细胞移植方法的镶嵌式的血运重建治疗,可减少并发症的发生,并使血管通畅,降低截肢平面,加快创面愈合,提高保肢率,治疗效果显著.
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