雷米芬太尼复合丙泊酚麻醉在鼾症手术中的应用

摘要

Objective: To study the application of remifentanil combined with propofol anesthesia in snoring surgery. Methods:124 cases of patients with snoring surgery were accepted operation in our hospital from June 2011 to June 2015 as objects. According to the random number table method, 124 cases of patients were divided into observation group ( 62 cases) and the control group ( 62 cases) , and the control group was given fentanyl and propofol combined anesthesia, patients in the observation group was given remifentanil com-bined with propofol anesthesia in operation, compared two groups of patients with anesthesia recovery related indicators, different period ( T0:before anesthesia;T1:the operation began;T2:5 min after the start of sur-gery;T3:30 min after the start of surgery;T4:operation finished) of blood pressure and heart rate, and pain condition after anesthesia . Results:The recovery time, pull tube time and question and answer pertinent time of patients in observation group were significantly less than the control group, the difference was statistically significant (P < 0.05). The levels of SBP, DBP, HR in T2 and SBP, DBP in T3 of the observation group were significantly lower than those in the control group ( P <0.05) . Compared with the control group, the lev-el of observation group’s T1~ T3 level of SBP, T1 level of DBP and T1~ T2 level of HR were significantly low-er than that of T0;T1 of SBP, DBP and HR levels were significantly lower than that at T0 in control group, the difference was statistically significant ( P <0.05) . There was no significant difference of the pain condition be-tween the two groups ( P > 0. 05 ) . Conclusion: Remifentanil and propofol compound anesthesia effect is smooth, and in early awake extubation, with high security, it is worth to be promoted.%目的：：研究雷米芬太尼复合丙泊酚麻醉在鼾症手术中的应用效果。方法：选择2011年6月至2015年6月在我院接受手术治疗的鼾症患者124例实施研究。根据数字随机表法将124例患者分成观察组( n＝62)及对照组( n＝62)两组，对照组术中给予芬太尼与丙泊酚的复合麻醉，观察组术中给予雷米芬太尼与丙泊酚的复合麻醉，对比两组患者的麻醉恢复相关指标，不同时期( T0：麻醉之前；T1：手术开始；T2：手术开始后的5min；T3：开始后30min；T4：手术完成)的血压及心率，以及麻醉苏醒后的疼痛情况。结果：观察组患者的苏醒时间、拔管时间以及答问切题时间均分别显著少于对照组，差异有统计学意义( P<0.05)。组间相比，观察组T2的SBP、DBP 及HR水平及T3的SBP、DBP 水平均分别显著低于对照组，差异有统计学意义( P<0.05)。组内相比，观察组T1~T3的SBP 水平、T1的DBP 水平及T1~T2的HR水平均分别显著低于T0的水平，对照组T1的SBP、DBP 及HR水平均分别显著低于T0的水平，差异有统计学意义(P<0.05)。两组麻醉苏醒后的疼痛情况相比，差异无统计学意义(P>0.05)。结论：雷米芬太尼与丙泊酚的复合麻醉产生的麻醉效果平稳，且可在早期时进行清醒拔管，安全性较高，值得推广。