冠心病患者EATV与冠状动脉斑块稳定性的关系

摘要

目的:研究冠心病患者心外膜脂肪体积(EATV)对冠状动脉斑块稳定性的影响.方法:选择从2014年5月到2016年10月在广西医科大学第三附属医院就诊的430例疑似冠心病患者.分析患者EATV与冠状动脉斑块的关系,对比不同斑块类型患者的EATV,不同EATV的有斑块组患者冠状动脉斑块稳定情况,以及不同EATV患者经血管内超声(IVUS)诊断的斑块相关指标.结果:有斑块组EATV≥85mL的发生率高于无斑块组,差异有统计学意义(P<0.05).不同斑块类型患者的EATV比较差异无统计学意义(P>0.05).有斑块组EATV≥85mL的不稳定斑块发生率高于EATV<85mL,差异有统计学意义(P<0.05).EATV≥85mL者的斑块、脂质及坏死的体积均大于EATV<85mL者,差异有统计学意义(P<0.05).结论:冠心病患者EATV对于其冠状动脉斑块稳定性具有较大的影响,且EATV越高影响越大.%Objective:To study the effects of epicardial adipose tissue volume( EATV) on coronary ar-tery plaque stability in patients with coronary heart disease. Methods: Selected 430 patients suspected with coronary heart disease in The Third Affiliated Hospital of Guangxi Medical University from May 2014 to Octo-ber 2016. Analyzed the relationship between EATV and coronary artery plaque, and compared the EATV in patients with different plaque types,coronary artery plaque stability status of patients with different EATV in plaque group,as well as plaque related indicators diagnosed by intravenous ultrasound ( IVUS) in patients with different EATV. Results:The incidence rate of EATV≥85mL in plaque group was significantly higher than non plaque group( P<0.05) . There was no significant difference on EATV among patients with different plaque types( P>0. 05 ) . The incidence rate of unstable plaque of EATV≥85mL was significantly higher than the EATV<85mL in plaque group ( P<0.05);The sizes of the plaque,lipid and necrotic in patients with EATV≥85mL were significantly higher than EATV<85mLt ( P<0.05) . Conclusion:EATV has great influence on the coronary artery plaque stability in patients with coronary heart disease, and the higher the level of EATV, the greater the impact.