4-（2-（二乙胺基）乙基）苯基硼酸的合成研究

摘要

Compounds of arylboronic acid have the advance of low toxicity, good thermal stability, compatibility and functional groups on water, air insensitivity, and so on. 4-(2-( diethylamino) ethyl) phenyl acid is quite important as an important intermediate in organic synthesis. The target compound was synthesized after reduction, acylation, hydrolysis three-step reaction with the 4-bromophenylacwtic acid as the lead compound, and its structure was tested by 1 H NMR. As a new compound in the market, there are good prospects for the study.%芳基硼酸类化合物具有低毒性，良好的热稳定性，官能团兼容性及对水、空气不敏感等优点。4-(2-(二乙胺基)乙基)苯基硼酸作为一种重要的中间体，在有机合成中的应用相当广泛。以对溴苯乙酸为原料，经还原、酰化、水解三步反应，合成目标化合物，并经过1 H NMR进行结构表征。目标化合物作为市场一种新的化合物，有很好的研究前景。