大隐静脉高位结扎联合聚桂醇硬化剂治疗下肢静脉曲张的临床效果

摘要

Objective To investigate the clinical effect of high ligation of great saphenous vein combined with polycinnamol sclerosing agent on the lower extremities with varicosity.Methods Sixty cases of varicose great saphenous vein were randomly divided into observation group and control group,with 30 cases in each group.The patients in the observation group were treated with high ligation of great saphenous vein combined with polycinnamol sclerosing agent,while the patients in the control group were treated with traditional high ligation and dissection of great saphenous vein.The operation-related indexes,postoperative complications,venous clinical severity score(VCSS) and postoperative recurrence were compared between the two groups.And the Visual Analogue Scale(VAS) score was used to observe pain state of patients in the two groups after 12,24,48 and 72 hours of operation.Results The observation group had less operation duration,intraoperative blood loss,postoperative hospital stay and hospitalization costs,lower incidence rate of overall postoperative complications,and less duration to ambulation after operation compared to the control group(P<0.05);at each postoperative time porint,the VAS score in the observation group was lower than that in the control group(P<0.05),the VAS score changed with time in both groups(P<0.05),and there was an interaction effect between group and time(P<0.05);no significant differences were observed in the postoperative VCSS score or recurrence rate between the two groups(all P>0.05).Conclusion High ligation of great saphenous vein combined with polycinnamol sclerosing agent has definite effects,faster recovery after operation,mild pain,and less adverse reactions in the treatment of lower extremities with varicosity.%目的 探讨大隐静脉高位结扎联合聚桂醇硬化剂治疗下肢静脉曲张的临床疗效.方法 60例大隐静脉曲张患者随机分为观察组及对照组,每组30例.观察组患者采用大隐静脉高位结扎联合聚桂醇硬化剂治疗,对照组患者采用传统大隐静脉高位结扎剥脱术治疗.比较两组患者手术相关指标、术后并发症、静脉临床严重程度评分(VCSS)、术后复发情况以及术后12 h、24 h、48 h及72 h视觉疼痛模拟量表(VAS)评分.结果 观察组患者手术时间、术中出血量、术后住院时间、住院费用及术后总并发症发生率均少于或低于对照组(P<0.05),且术后下床活动时间早于对照组(P<0.05);术后各时点观察组VAS评分均低于对照组(P<0.05),两组的VAS评分均有随时间变化的趋势(P<0.05),分组与时间有交互效应(P<0.05);两组患者术后VCSS评分及复发率比较,差异均无统计学意义(均P>0.05).结论 大隐静脉高位结扎联合聚桂醇硬化剂治疗下肢静脉曲张效果确切,患者术后恢复快、痛苦轻、不良反应少.