Molecular analysis of signaling events mediated by the cytoplasmic domain of leukemia inhibitory factor receptor α subunit

摘要

A chimeric receptor (130/190) containing the cytoplasmic region of leukemia inhibitory factor receptor a sub-unit (LIFRα, or gp190) and the extracellular transmembrane region of gp130 was generated. Expressed of the 130/190 chimera in HL-60 cells to induced