Effect of Egyptian Date Palm Pollen (Phoenix dactylifera L.) and Its Hydroethanolic Extracts on Serum Glucose and Lipid Profiles in Induced Diabetic Rats

摘要

Diabetes is a major health global problem that has reached alarming levels. The present study aims for studying the effect of date palm pollen (Phoenix dactylifera L.) El-Hayani cultivar on serum glucose and lipids profile in induced diabetic male albino rats. Palm pollen chemically analyzed besides chemical constituents, mineral contents, polyphenols and flavonoids. Male Albino rats (36 rats weight 170-190 gm) were divided into 6 groups. 1: Normal control (-), 2: Alloxanized diabetes control (+) (150 mg/Kg rat body weight). Diabetic groups 3 and 4 had 0.5%, 1.0% date palm pollen, respectively, also diabetic groups 5 and 6 had 100 ppm, 200 ppm date palm pollen extract, respectively. At the end of the experiment (4 weeks) rats were fasted overnight and anesthetized and blood samples were taken for analysis of serum glucose, lipids profile and renal-hepatic function parameters, relative organ weight data obtained are statistically analysis. Results showed that the major polyphenolic components were that e-vanillic acid (16.33 mg/100 g), pyrogallol (15.02 mg/100 g), epicatechin (11.04 mg/100 g), catechin (10.96 mg/100 g). While, date palm pollen was rich in hesperidin (8.84 mg/100 g), Kaempferol 3,2 p-coumaroyl glucose (6.92 mg/100 g), hesperitin (5.10 mg/100 g), rutin (3.11mg/100 g) as flavonoids components. Date palm pollen has high content of protein, calcium and iron (30.87 g/100 g, 510.82 and 236.50 mg/100 g), respectively. Also, serum glucose decreased significantly in diabetic groups (3, 4, 5 and 6, respectively) (179.47, 137.80, 156.77, 145.47 mg/100 mL, respectively). Lipids profile, renal and liver functions were improved significantly (P which had date palm pollen or its extracts. It is concluded that the dried date palm pollen 1% in the diet and 200 ppm extract are more effective compared with controlling diabete