Approximately in the late-December of 2019, the coronavirus disease outbreak took place in China. COVID-19 (Coronavirus Disease 2019) is contagious and detrimental to the human body, which can even lead to death. As a result, the understanding of COVID-19 has become especially important. This paper studies four cases of anomalous disease-spreading in China (Guangdong Province, Heilongjiang province, Tianjin municipality, and Guizhou province) and analyzes four influencing factors of the transmission (temperature, transportation and passenger traffic volume, household size and distribution, and awareness). Major conclusions in this paper are as follows. Transportation and passenger traffic volume and the number of larger households are positively related to the extent of disease-spreading;the degree of awareness is negatively associated with the extent of disease-spreading. Provinces, municipalities, and autonomous regions with a more urbanized distribution of households are prone to experience a greater extent of disease transmission. Although the novel coronavirus prefers colder environment, temperature appears to be a secondary influencing factor, as regions with negative temperatures have fewer diagnoses. Disease transmission in Guangdong province is caused by a high volume of passenger traffic, large and urbanized households, and low awareness. Heilongjiang province is mainly a result of high passenger traffic volume, long travelling trips, and low public awareness. Guizhou province is benefited from high awareness, limited passenger volume, and scattered households. Tianjin municipality is protected from the severe disease-spreading owe to its beneficial temperature, low land transportation volume, and high public and government awareness.
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