CT对颈胸部恶性淋巴瘤治疗疗效的评估

摘要

目的 评价CT对颈胸部恶性淋巴瘤治疗疗效判断的准确性以及在其随访中的价值;初步探讨恶性淋巴瘤强化程度与治疗疗效之间的关系.方法 收集经病理证实的22例颈、胸部恶性淋巴瘤,所有患者在化疗前及化疗后均行多次CT扫描,比较淋巴瘤治疗前后的变化情况;将恶性淋巴瘤分为轻度强化、中度强化、明显强化,比较不同强化程度淋巴瘤的化疗疗效.结果 22例患者三个月内均复查,其中2例完全缓解,15例部分缓解,5例无变化.本组行CT平扫加增强扫描的21例患者中,7例淋巴瘤为轻度强化,三个月内复查,有 5例部分缓解,1例完全缓解,1例无变化;13例淋巴瘤为中度强化,三个月内复查有 10例部分缓解,1例完全缓解,2例无变化;1例淋巴瘤明显强化,复查显示部分缓解.统计结果显示轻度强化与中度强化淋巴瘤的化疗疗效间无显著性差异.结论 作为一种无创、简便的方法,CT能对恶性淋巴瘤的治疗疗效作出较为准确的评价.%Objective To evaluate the value of CT in the therapy effect of cervical and thoracic malignant lymphoma as well as in the follow-up, to discuss the relationship between the enhancement degree of lymphoma leasions and the therapy effect. Methods 22 cases of cervical and thoracic malignant lymphoma were study retrospectively. CT scanning was performed in all patients before therapy and after therapy. The change of lymphoma was compared before chemical therapy and after chemical therapy. According to the enhancement degree, malignant lymphoma was divided into slight enhancement, moderate enhancement and obvious enhancement. The therapy effect of lymphoma of different enhancement was compared. Results CT follow-up were performed in 22 patients in 3 months. 2 cases were complete remission, 15 cases were partial remission, 5 cases were unchanged. 7 cases were slight enhancement in 21 patients who performed both plain scanning and enhanced scanning, 13 cases were moderate enhancement and 1 case were obvious enhancement. There was no difference in the therapy effect between the slight enhancement lymphoma and the moderate enhancement lymphoma. Conclusion As an invasive and simple method, CT can provide accuracy information for the therapy effect of malignant lymphoma.