急诊应用胺碘酮治疗快速性心律失常的临床分析

摘要

Objective To investigate the safety and effect of amiodarone for treating various types of fast arrhythmia in the e-mergency patients .Methods 180 patients with fast arrhythmia in the emergency department of the Wushan County People s Hospital from 2005 to 2009 were divided into the supraventricular group (n-140) and the ventricular group(n=40) according to the causes of arrhythmia .The supraventricular group was subdivided into the observation group (supraventricular group A) treated by amiodarone and the control group (supraventricular group B) treated by lanatoside ,70 cases in each subgroup ; the ventricular group was subdivided into the observation group (ventricular group A) treated by amiodarone and the control group (ventricular group B) treated by lidocaine ,20 cases in each subgroup .The clinical observation and the efficacy analysis were performed in each group Re-sults The effective rate in the supraventricular group A was higher than that in the supraventricular group B ,while the rate of adverse reactions was lower than the supraventricular group B .The effective rate of the ventricular group A was higher than that of the ventricular group B ,while the rate of adverse reactions was lower than the ventricular group B .The total effective rate in observation groups was higher than that in the control groups with statistical difference (P<0 .05) .Conclusion Amiodarone is superior to cedilanid and lidocaine in the overall treatment effect with less adverse reactions .Using amiodarone for treating various types of rapid arrhythmia in emergency has obvious effect and high safety ,which is worth popularizing .%目的 探讨应用胺碘酮治疗急诊患者中各种不同类型的快速性心律失常的安全性和有效性.方法 将2005～2009年来巫山县人民医院急诊科就诊的快速性心律失常患者180例,根据其心律失常原因不同将其分为室上性组(n=140)和室性组(n=40),再从室上性组中分出采用胺碘酮治疗的观察组(室上性A组)和采用毛花苷C治疗的对照组(室上性B组),每组70例;从室性组中分出采用胺碘酮治疗的观察组(室性A组)和采用利多卡因治疗的对照组(室性B组),每组20例.对各组进行临床观察和疗效分析.结果 室上性A组的有效率要高于室上性B组,不良反应率要低于室上性B组;室性A组的有效率要高于室性B组,不良反应率要低于室性B组;观察组的整体有效率要高于对照组,差异有统计学意义(P<0.05).结论 使用胺碘酮治疗的患者整体治疗效果要优于毛花苷C、利多卡因治疗的患者,并且不良反应率更低,在急诊中应用胺碘酮治疗各种不同类型的快速性心律失常效果明显,安全性高,值得推广.