Studies of ATP sensitive potassium channels on 6 - hydroxydopamine and haloperidol rat models of Parkinson＇ s disease： Implications for treating Parkinson＇ s disease？

摘要

Parkinson' s disease is a common neurodegenerative movement disease that affects more than 1% of the elderly population, characterized by a preferential loss of the dopaminergic neurons of the substantia nigra pars compacta. Although during the past score, major biochemistry process such as mitochondrial dysfunction, oxidative stress and glutamate