毛鱼藤根中的鱼藤酮类化合物Ⅱ

摘要

目的:对广东产毛鱼藤(Derns elliptica(Roxb.)Benth.)根的化学成分进行研究.方法:运用多种层析手段进行分离纯化,通过波谱解析和理化鉴别进行结构鉴定.结果:分离鉴定了7个鱼藤酮类化合物,分别为:7'-羟基-6a,12a-脱氢鱼藤素(7'-hyaroxy-6a,12a-dehydrodeguelin,1)'6-羟基-6a,12a-脱氢鱼藤素(6-hydroxy-6a,12a-dehydrodeguelin,2),(6aR,12aR,4'R,5'S)-4',5'-dihydro-4,5'-dihydroxytephrosin(3),6'-羟基-6a,12a-脱氢鱼藤酮(6'-hydroxy-6a,12a-dehydrorotenone,4),(-)-rotoic acid(5),(-)-deguoic acid(6),12-deoxo-12a.acetoxyelliptone(7).结论:化合物1为新化合物,化合物2～6为首次从鱼藤属中分得,化合物7为首次从毛鱼藤中分得.%AIM:To study the chemical constituents of Derris elliptica (Roxb.) Benth.METHOD:The chemical constituents were isolated by various chromatographic methods,and the chemical structures were elucidated on the basis of spectral analysis.RESULTS:Seven rotenoids were obtained and their structures were identified as 7"-hydroxy-6a,12a-dehydrodeguelin (1),6-hydroxy-6a,12a-dehydrodeguelin (2),(6aR,12aR,4'R,5'S)-4',5'-dihydro-4',5'-dihydroxytephrosin (3),6"-hydroxy-6a,12a-dehydrorotenone (4),(-)-rotoic acid (5),(-)-deguoic acid (6),12-deoxo-12a-acetoxyelliptone (7).CONCLUSION:Compound 1 is a new compound,compounds 2-6 were isolated from this genus for the first time,and compound 7 was isolated from Derris elliptica (Roxb.)Benth.for the first time.