秃叶黄皮树果实中的三萜化学成分

摘要

AIM:To investigate the chemical constituents from the fruits of Phellodendron chinense Schneid var.glabriusculum Schneid.METHODS:The constituents of ethyl acetate-soluble portions in the 95% ethanol extract were isolated and purified by various chromatographic methods.Their structures were identified by their physicochemical characteristics and spectral data.RESULTS:Eight known compounds were isolated and identified as piscidinol A(I),phellochin(2),niloticin (3),dihydroniloticin (4),21,23-epoxy-21a,24,25-trihydroxytirucalla-7-en-3-one (5),2a,25-dimethylmelianodiol-[(21R,23R)-epoxy-24-hydroxy-21a,25-methoxy]tirucalla-7-en-3-one (6),boujotinolone A (7),3-ketooleanane(8).CONCLUSION:Compounds 5-8 are isolated from Phellodendron chinense Schneid var.glabriusculum Schneid.for the first time.%目的:研究秃叶黄皮树(Phellodendron chinense var.glabriusculum Schneid)果实中的化学成分.方法:对秃叶黄皮树果实95%乙醇提取物的乙酸乙酯部分进行色谱分离,根据光谱数据和理化性质确定各化合物的结构.结果:分离得到8个已知化合物,分别为piscidinol A(1),phellochin(2),niloticin(3),dihydroniloticin(4),21,23-epoxy-21a,24,25-trihydroxytimcalla-7-en-3-one(5),2a,25-dimethylmelianodiol-[(21R,23R)-epoxy-24-hydroxy-21a,25-methoxy]tirucaUa7-en-3-one(6),boujofinolone A(7),3-ketooleanane(8).结论:化合物5～8为首次从秃叶黄皮树分离得到.