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Coronary bifurcation lesions treated with double kissing crush technique compared to classical crush technique: serial intravascular ultrasound analysis

机译:与传统挤压技术相比,双吻挤压技术治疗冠状动脉分叉病变:连续血管内超声分析

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Background The double kissing (DK) crush technique is a modified version of the crush technique.It is specifically designed to increase the success rate of the final kissing balloon post-dilatation,but its efficacy and safety remain unclear.Methods Data were obtained from the DKCRUSH-I trial,a prospective,randomized,multi-center study to evaluate safety and efficacy.Post-procedural and eight-month follow-up intravascular ultrasound (IVUS) analysis was available in 61 cases.Volumetric analysis using Simpson's method within the Taxus stent,and cross-sectional analysis at the five sites of the main vessel (MV) and three sites of the side branch (SB) were performed.Impact of the bifurcation angle on stent expansion at the carina was also evaluated.Results Stent expansion in the SB ostium was significantly less in the classical crush group ((53.81±13.51)%) than in the DK crush group ((72.27±11.46)%) (P=-0.04).For the MV,the incidence of incomplete crush was 41.9% in the DK group and 70.0% in the classical group (P=-0.03).The percentage of neointimal area at the ostium had a tendency to be smaller in the DK group compared with the classical group ((16.4±19.2)% vs.(22.8±27.1)%,P=-0.06).The optimal threshold of post-procedural minimum stent area (MSA) to predict follow-up minimum lumen area (MLA) <4.0 mm2 at the SB ostium was 4.55 mm2,yielding an area under the curve of 0.80 (95% confidence interval:0.61 to 0.92).Conclusion Our data suggest that the DK crush technique is associated with improved quality of the final kissing balloon inflation (FKBI) and had smaller optimal cutoff value of post-procedural MSA at the SB ostium.
机译:背景技术双吻(DK)挤压技术是对挤压技术的改进版本,专门设计用于提高最终亲吻气球扩张后的成功率,但其有效性和安全性尚不清楚。 DKCRUSH-I试验是一项前瞻性,随机,多中心研究,以评估安全性和有效性。有61例患者进行了术后和八个月的后续血管内超声(IVUS)分析。在红豆杉中使用Simpson方法进行容量分析支架,并在主血管(MV)的五个部位和侧支(SB)的三个部位进行横截面分析。还评估了分叉角度对支架在支架上扩张的影响。 SB粉碎组在经典粉碎组中(53.81±13.51)%显着低于DK粉碎组(72.27±11.46)%(P = -0.04)。 DK组为41.9%,我为70.0%在经典组中(P = -0.03)。与经典组相比,DK组的新生内膜面积百分比趋于较小((16.4±19.2)%vs.(22.8±27.1)%, P = -0.06)。在SB开口处预测术后最小管腔面积(MLA)<4.0 mm2的最佳术后阈值(MSA)为4.55 mm2,曲线下面积为0.80( 95%的置信区间:0.61至0.92)。结论我们的数据表明DK压碎技术与最终接吻球囊充气(FKBI)的质量提高相关,并且在SB口的术后MSA的最佳截止值较小。

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