2014～2016年广州市屠宰场分离沙门氏菌血清学鉴定和耐药性分析

摘要

2014～2016年从广州市屠宰场分离沙门氏菌151株,鉴定出12种血清型,前3位优势血清型分别为德尔卑沙门氏菌、罗森氏沙门氏菌、鼠伤寒沙门氏菌.采用微量肉汤稀释法测定分离菌株对13种抗菌药物的敏感性.结果显示,沙门氏菌对四环素、多西环素、磺胺异恶唑、氨苄西林、大观霉素的耐药率都在60％以上,对奥格门丁、恩诺沙星、氧氟沙星、头孢噻呋、多粘菌素E敏感(耐药率≤16％).多重耐药率为79.20％.研究表明,沙门氏菌对部分药物耐药性较严重,亟需加强养殖业抗菌药物的合理应用以控制耐药性的发展.%A total of 151 Salmonella strains were isolated from the slaughter houses in Guangzhou from 2014 to 2016, and 12 serotypes were identified.Among the strains, S.derby, S.rissen and S.typhimurium were top 3 serotypes.Antimicrobial susceptibility among Salmonella isolates against 13 antimicrobial drugs was performed using microdilution method.The results showed that percents of resistance among the strains were more than 60％ for tetracycline, doxycycline, sulfurazole, ampicilin, and spectinomycin, The strains were sensitive to amoxycilin/elavulanic acid, enrofloxacin, ofloxacin, ceftiofur, and polymyxin E (resistance rates were lower than 16％ for these drugs).The multidrug-resistance rate was 79.20％.The researches show that Salmonella strains were seriously to some drugs.It is urgent that the domestic industry should reasonably use antimicrobials to control the development of antimicrobial resistance.