有限元分析运用于股骨头坏死诊断与治疗应用的最新进展

摘要

背景：目前有限元分析技术已可以完成建模，预测诊断，治疗的设计，以及手术方案等功能，并应用于股骨头坏死领域。目的：总结和汇总有限元分析对在股骨头坏死生物力学领域的最新临床与实验研究进展。　　方法：由第一作者通过计算机检索PubMed，Google，SpringerLink，CNKI等数据库在2010年1月至2015年12月的已发表文献。检索式为(finite element analysis OR finite elment) AND ；(osteonecrosis OR osteonecrosis of femoral head)或(有限元分析 OR 有限元)AND(骨坏死OR股骨头坏死)。纳入原始文献内容与文章主旨紧密相关，原始文献有可靠依据与主题，原始文献观点及数据分析充分，活体与离体研究。　　结果与结论：共纳入27篇。文章综述近5年来有关股骨头坏死中有限元分析应用文献，总结发现目前最新的有关运用有限元进行股骨头坏死建模可行性分析、特征病理的预测和诊断、手术治疗的创新技术辅助等发展水平，从而明确有限元分析在股骨头坏死的诊断和治疗未来发展方向。%BACKGROUND:At present, finite element analysis technology can set up the model, predict diagnosis, treatment design, as wel as surgical plan, and can be used in the treatment of necrosis of femoral head. OBJECTIVE:To sum and discuss recent progress in clinical and experimental research regarding biomechanical study in osteonecrosis of femoral head by using finite element analysis. METHODS:A computer-based retrieval was performed by the authors (Hong Guo-ju and Zhou Guang-quan) in PubMed, Google, SpringerLink, ChinaNational Knowledge Infrastructure databases for literatures published from January 2010 to December 2015. The key words were“(finite element analysis OR finite element) AND (osteonecrosis OR osteonecrosis of femoral head)”. Inclusive criteria:studies with contents closely related to this paper;original papers with reliable topics and evidence;or papers with clear points and al-round analysis and both studies in vitro and in vivo. RESULTS AND CONCLUSION:A total of 27 studies were included. The articles in the latest five years related to femoral head osteonecrosis and finite element analysis application were concentrated on. We summarized the latest research progress and problems, including the applied research carried out in the femoral head osteonecrosis clinical cases, innovational skil s, so as to point out the direction of future research in the finite element analysis.