N-碘代琥珀酰亚胺促进胺化反应合成新型三唑-4-噁唑啉衍生物

摘要

2-( Benzoxyethyl)-1-aryl(or methyl)-3-aryl-1H-1-(2-triazole-5-yl) acetamide and N-dioxy-ethyl-1-aryl(or methyl)-1H-1.2.4-triazole-5-amine derivatives were used as starting materials, N-io-dosuccinimide as oxidant, twelve triazole-4-oxazoline derivatives(2a～2g and 4h～4l) were synthe-sized by intramolecular amination under visible light irradiation.The structures were characterized by 1H NMR, 13C NMR and HR-MS(ESI).%以2-(苄氧)-N-(1-芳基(或甲基)-3-芳基-1H-1,2,4-三唑-5-基)乙酰胺和N-2-(苄氧乙基)-1-芳基(或甲基)-1H-1.2.4-三唑-5-胺衍生物为主要原料,N-碘代丁二酰亚胺为氧化剂,在可见光照射下发生分子内胺化反应,合成了12个新型的三唑-4-噁唑啉衍生物(2a～2g和4h～4l),其结构经1H NMR, 13C NMR和HR-MS(ESI)表征.