Objective:To investigate the effect of low frequency repetitive transcranial magnetic stimulation (rTMS) combined with occupational therapy on the recovery of upper limb function less than 3 months after a stroke. Methods:Sixty stroke patients were randomly divided into a study group and a control group, with 30 in each group. Both groups received the routine occupational therapy. The study group was treated with 1 Hz rTMS additionally. Before and after treatment, the upper extremity portion of the Fugl-Meyer assessment (FMA) was performed along with a functional test for the hemiplegic extremity (FTHUE). The modified Barthel Index (MBI) was also quantified. Results:During the treatment, 2 patients in the study group and 1 patient in the control group dropped out. No serious side-effect was found. After the intervention, both groups had significantly improved their average FMA, FTHUE and MBA scores, with the average scores of study group being significantly higher than those of control group. Conclusions:Occupational therapy in combination with rTMS can improve motor recovery after stroke.%目的:探讨低频重复经颅磁刺激 (rTMS) 联合作业治疗对脑卒中恢复期患者上肢功能恢复的影响.方法:将60例脑卒中恢复期患者随机分为治疗组和对照组各30例.对照组接受常规的作业治疗, 治疗组在常规作业治疗的同时给予1Hz的rTMS治疗.在治疗前及治疗4周后采用上肢Fugl-Meyer评分 (FMA) 、偏瘫上肢功能测试-香港版 (FTHUE-HK) 及改良的Barthel指数 (MBI) 对患者上肢功能进行评定.结果:治疗4周后, 2组的FMA、FTHUE-HK评分和MBI均较治疗前明显提高 (均P＜0.05), 且治疗组各项评分均高于对照组 (均P＜0.05) .结论:rTMS联合作业治疗可改善脑卒中恢复期患者上肢运动功能, 提高日常生活活动能力.
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