结膜重度非典型增生局部癌变7例临床分析

摘要

目的 探讨眼结膜重度非典型增生局部癌变的临床特点及其治疗和预后.方法 回顾性分析我院眼科术后经病理确诊为结膜重度非典型增生局部癌变7例患者,随诊1～15年,平均98个月.结果 7例结膜重度非典型增生局部癌变,其中3例行局部病变切除手术,4例行眶内容物剜出术.术后复发2例,均为局部病变切除手术后局部复发,术后复发比例28.57％ (2/7),死亡0例(0/7),未见其它部位转移.复发病例再行眶内容物剜出术.结论 结膜重度非典型增生局部癌变的预后与解剖部位、累及范围、首次治疗方案等有关.早期诊断和选择最佳治疗方案是改善生存质量的重要手段,可致很好预后.%Objective To investigate the clinical characteristics,treatment and prognosis of conjunctival severe dysplasia localized cancer.Methods 7 cases of conjunctival severe dysplasia in patients with localized cancer based on postoperative pathological diagnosis were analyzed,followed up for 1～15 years,an average of 98 months,retrospectively.Results In 7 cases,3 of them underwent partial resection of lesions,4 cases of orbital contents enucleation.Postoperative local recurrence occured in 2 local lesion excision cases,secondary surgerg was taken (orbital contents enucleation),recurrence rate was 28.57％ (2/7),no death case(0/7),no other part of the transfer.Conclusion Prevention of conjunctival severe atypical hyperplasia partial canceration was affected by many aspects,in cluding anatomic site,involving scope of the lesion,the first treatment,etc.Early diagnosis and choosing a best treatment are important to improve the quality of life,with good prognosis.