绝经后骨质疏松症患者肌力与骨密度的相关性研究

摘要

Objective To explore the relationship between muscle strength and bone mineral density ( BMD) in postmenopausal osteoporotic patients. Methods A total of 144 patients with osteoporosis, aging from 50 to 75 years old, were selected from October 2010 to January 2011 in Guangdong province. According to TCM syndrome differentiation, they were divided into kidney Yang failure group, liver and kidney Yin deficiency group, spleen and kidney Yang failure group, and Qi stagnancy and blood stasis group. Total muscle strength detection was performed in patients of 4 groups. The database was established using a SPSS 16�0 software. Results The maximal BMD of L1⁃4 was found in kidney Yang failure group, then in spleen and kidney Yang failure group, and the minimal strength was found in Qi stagnancy and blood stasis group. The maximal muscle strength was found in kidney Yang failure group, then in the spleen and kidney Yang failure group, and the minimal muscle strength was found in Qi stagnancy and blood stasis group. The comparison between kidney Yang failure group and spleen and kidney Yang failure group was not significantly different ( P>0�05 ) . The comparison between the other 3 groups and Qi stagnancy and blood stasis group was statistically significant (P<0�05). The waist back muscle strength was positively correlated with L1⁃4 average BMD. Conclusion BMD decreases from high to low in kidney Yang failure group, spleen and kidney Yang failure group, liver and kidney Yin deficiency group, and Qi stagnancy and blood stasis group, indicating that osteoporosis is more serious in Qi stagnancy and blood stasis group than in other 3 groups. Following the development of osteoporosis, the muscle strength also decreases, indicating that the waist muscle strength is positively correlated with BMD.%目的：探讨绝经后骨质疏松症患者腰部背伸肌力与骨密度的关系。方法选择自2010年10月到2011年1月广东省部分地区行骨密度检测的144例女性骨质疏松症患者，年龄分布在50岁～75岁之间。根据中医辨证分型依次分为：肾阳虚衰组、肝肾阴虚组、脾肾阳虚组及气滞血瘀组。4组患者均行腰部背伸肌力检测，最后数据用SPSS16�0统计软件建立数据库，进行统计分析。结果4组中L1⁃4平均BMD比较，肾阳虚衰组BMD较大，脾肾阳虚组次之，气滞血瘀组BMD值较小，4组之间两两比较均有统计学意义（P＜0�05）。4组中腰部背伸肌力值比较，肾阳虚衰组肌力较大，脾肾阳虚组次之，气滞血瘀组肌力较小，肾阳虚衰组与脾肾阳虚组比较没有明显统计学差异（P＞0�05），3组与气滞血瘀组比较均有统计学意义（P＜0�05）；腰部背伸肌力与L1⁃4平均BMD值呈正相关。结论4组中骨密度由高到低依次为肾阳虚衰、脾肾阳虚、肝肾阴虚、气滞血瘀，说明气滞血瘀型骨质疏松较其他3组骨质疏松严重。随着骨质疏松的发展，腰部背伸肌力日益减小，说明腰部背伸肌力的变化与骨密度呈正相关关系。