目的 探讨亚临床甲状腺功能异常患者的病因构成.方法 回顾性分析2326例患者甲状腺细针穿刺的临床资料及其细胞病理诊断结果,临床资料包括甲状腺功能及甲状腺自身抗体检测、甲状腺超声检查等.结果 亚临床甲状腺功能异常的患者274例,占11.8％,其中,亚临床甲状腺功能亢进患者112例,占4.8％,亚临床甲状腺功能减退患者162例,占7.0％.桥本甲状腺炎是亚临床甲状腺功能减退最常见的病因,而结节性甲状腺肿是亚临床甲状腺功能亢进最常见的病因.结论 在亚临床甲状腺功能异常的患者中,桥本甲状腺炎和结节性甲状腺肿是主要的两大病因,甲状腺细针穿刺对于亚临床甲状腺功能异常病因的诊断具有重要的临床价值.%Objective To determine the etiolgy of subclinical thyroid dysfunction in patients performed by fine - needle aspiration biopsy ( FNAB) . Methods 2326 FNABs were performed between 2005 - 2011 and related clinical records were retrospectively evaluated. Clinical data included thyroid function tests, immunological studies and ultrasound of the thyroid. Results We identified 274 cases with subclinical thyroid dysfunction, a prevalence of 11. 8% , including 112 subclinical hyperthyroidism cases (4.8%) and 162 subclinical hypothyroidism cases (7.0%). Hashimoto' s thyroiditis was the moat common cause of subclinical hypothyroidism and multinodular goiter was the most common cause of subclinical hyperthyroidism. Conclusion Hashimoto' s thyroiditis and multinodular goiter were the most common causes of subclinical thyroid dysfunction. FNAB is a very reliable diagnostic method for the evaluation of etiology of subclinical thyroid dysfunction.
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