引起真菌性鼻-鼻窦炎的危险因子分析并与慢性鼻-鼻窦炎的临床表现进行对比

摘要

目的：探讨和分析真菌性鼻-鼻窦炎发病相关的危险因子和临床表现。方法：对2008年~2010年间在我院住院的80例慢性鼻-鼻窦炎患者进行对照研究。结果：慢性鼻-鼻窦炎相比,真菌性鼻-鼻窦炎组患者女性患者比较多,好发于40岁以的人群,病程在3年以内者较多,差异有统计学意义(P<0.05)。两组资料相比,真菌性鼻-鼻窦炎有统计学意义的临床症状为涕血。多因素Logistic回归分析结果显示其中涕血(β=4.76, OR=116.75)、钙化斑(β=4.35, OR=77.48)、单侧病变(β=2.83, OR=11.91)是高危险因子(OR值远大于1)。得到的回归方程为y=-8.35+1.24x1+0.52x2+1.32x3+4.35x4+4.76x5+2.83x6。结论：涕血是真菌性鼻-鼻窦炎的重要临床症状,单侧CT显示钙化斑是重要的影像学表现。%Objective:To analyze risk factors and clinical features of fungal rhinosinusitis.Methods:During 2008 to 2010,control study of 80 cases in our hospital.Results:Compared with chronic rhinosinusitis,fungal rhinosinusitis were female,over 40-year-old and course of disease<3years(P<0.05).Significant clinical symptom of fungal rhinosinusitis was haem-nasal discharge(P<0.05).The haem-nasal discharge(β=4.76,OR=116.75),calcified plaque(β=4.35,OR=77.48) and unilateral sinus lesion(β=2.83, OR=11.91)were risk factors of fungal rhinosinusitis(P<0.05).The logistic regression predictive equation for fungal rhinosinusitis was:y=-8.35+1.24x1+0.52x2+1.32x3+4.3 5x4+4.76x5+2.83x6,P=exp(y)/[1+exp(y)].Conclusion:Taem-nasal discharge is an important clinical symptoms of fungal rhinosinusitis and the unilateral presence of calcified plaque in CT scan is an important imaging finding.