宁泌泰胶囊联合左氧氟沙星片对慢性前列腺炎患者前列腺液中分泌型免疫球蛋白A的影响

摘要

Objectives:To investigate the effect of Ningmitai capsule combined with Ningmitai Tablets for intervention secretory immunoglobulin A in prostate fluid of chronic prostatitis patients.Methods:150 chronic pros-tatitis patients in our hospital from 2010 December to 2013 November were selected and randomly divided into con-trol group and observation group,75 cases in each group.Control group received Ningmitai tablets treatment.The observation group received Ningmitai tablets combined Ningmitai capsule.Results:The total effective rate of obser-vation group was 88% higher than the 73.3% of control group,with statistically significant difference (P <0.05). After the treatment,SIgA level in the prostatic fluid decreased.However,2 weeks,4 weeks,6 weeks and 8 weeks after the treatment,SIgA in prostatic fluid level of the observation group was lower than in the control group,with statistically significant difference (P <0.01).Conclusion:The higher value of Ningmitai capsule combined with Levofloxacin tablets in treatment of chronic prostatitis can significantly reduce the prostate fluid levels of SIgA, meanwhile significantly alleviate symptoms and clinical significance.%目的：评价宁泌泰胶囊联合左氧氟沙星片对慢性前列腺炎患者前列腺液中分泌型免疫球蛋白 A（SIgA）的影响。方法：选择于2010年12月至2013年11月在我院进行治疗的慢性前列腺炎患者150例，随机分成对照组和观察组，各75例。对照组：采用左氧氟沙星片进行治疗。观察组：采用左氧氟沙星片联合宁泌泰胶囊进行治疗。结果：观察组总有效率为88.0％优于对照组的总有效率73.3％，差异具有统计学意义（P ＜0.05）。治疗后，两组患者前列腺液中 SIgA 水平均存在一定程度的下降，但是观察组在治疗后2周、治疗后4周、治疗后6周以及治疗后8周的前列腺液中的 SIgA 水平均明显低于对照组，差异具有统计学意义（P ＜0.01）。结论：宁泌泰胶囊联合左氧氟沙星片在慢性前列腺炎的治疗中具有较高的应用价值，可以显著降低前列腺液中的 SIgA 水平，同时能够大幅改善缓解患者的症状，临床意义显著。