光电容积脉搏波特征参数与冠状动脉病变程度的相关性研究

摘要

Objective To study the correlation between characteristic parameters of photoplethysmography( PPG)and severity of coronary artery lesions.Methods Two hundred and twenty-six CHD patients who underwent CAG in our hospital from August 2018to November 2018were divided into single-vessel lesion group(n=55),double-vessel lesion group(n=74)and multi-vessel lesion group(n=97)according to their CAG.Their stiffness index(SI),crest time(CT),normalized crest time(NCT)and crest time ratio(CTR)were recorded by PPG and analyzed by correlation analysis.Results The SI was significantly different in single-vessel lesion group,double-vessel lesion group and multi-vessel lesion group(6.479±0.819m/s,6.692±1.051m/s and 6.943±1.096m/s,P=0.024).No significant difference was detected in CT,NCT and CTR among single-vessel lesion group,double-vessel lesion group and multi-vessel lesion group(P＞0.05).The SI was positively correlated with the severity of coronary artery lesions(r=0.162,P=0.015).Conclusion The SI is correlated with the severity of coronary artery lesions,which is of a certain value in predicting the severity of coronary artery lesions.%目的 探讨光电容积脉搏波(PPG)特征参数与冠状动脉病变程度的相关性.方法 选取2018年8～11月解放军总医院行冠状动脉造影(CAG)检查的冠心病患者226例,按CAG结果分为单支病变组55例、双支病变组74例和多支病变组97例.采集患者一般临床资料,行PPG检测,提取硬化指数(SI)、主峰时间(CT)、标准化主峰时间(NCT)和主峰时间比(CTR)等,进行相关性分析.结果 单支病变组、双支病变组和多支病变组SI比较,差异有统计学意义[(6.479±0.819)m/s vs (6.692±1.051)m/s vs (6.943±1.096)m/s,P=0.024];3组CT、NCT和CTR比较,差异均无统计学意义(P＞0.05).SI与冠状动脉病变程度呈正相关(r=0.162,P=0.015).结论PPG特征参数SI与冠状动脉病变程度有一定的相关性,可能对预测冠状动脉病变程度有一定的价值.