Two patients (one man with T2DM and another man with gastric ulcer) had postprandial symptoms of neuroglycopenia owing to endogenous hyperinsulinemic hypoglycemia after Roux-en-Y anastomosis surgery. There was no radiographic evidence of insulinoma. OGTT test showed the augmentation of insulin and C-P secretion. Hypoglycemic symptoms diminished after dietary modification and orglucosidase inhibitor such as voglibose.%接受Roux-en-Y胃空肠吻合术患者2例(术前T2DM及胃溃疡各1例),术后均出现发作性低血糖反应,OGTT显示餐后高胰岛素、C-P分泌及胰腺影像检查未见明显异常,予饮食调整联合α-糖苷酶抑制剂治疗均有效.
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