目的：探讨功能性消化不良（FD）患者不同胃区胃排空及胃内食物分布与症状之间的关系。方法采用实时超声检测73例FD患者和27例正常对照组胃排空功能，并调查73例FD患者的症状。结果 FD患者各胃区半排空时间均较正常对照组延长（P＜0.05），胃排空延迟率明显增加（P＜0.01）；远端胃半排空时间与早饱、体重指数呈正相关（P＜0.05）；全胃半排空时间与年龄呈负相关（P＜0.05）；分别对各胃区排空情况与症状进行Logistic回归分析，仅早饱与远端胃排空延迟相关（P＜0.05）；20 min、40 min近端胃面积，40 min全胃面积与上腹部烧灼感呈负相关（P＜0.05）；20 min、40 min远端胃面积与早饱呈负相关（P＜0.05）。结论 FD患者存在胃排空异常，远端胃排空情况与早饱存在相关性。%Objective To study relationship between gastric emptying on proximal stomach, distal stomach, total stomach and intragastric distribution and dyspepsia symptoms in patients with functional dyspepsia (FD). Methods A real-time ultrasonography was performed in 73 cases of FD patients and 27 healthy controls (HC). Dyspepsia symptoms were investigated by using a questionnaire. Results As compared with that in HC group, the half time of gastric emptying on proximal stomach (pT1/2), half time of gastric emptying on distal stomach (dT1/2) and gastric emptying half-time on total stomach (GT1/2) was prolonged significantly in FD (P<0.05).The delay rate of proximal stomach, distal stomach and total gastric was significantly increased (P<0.01). In FD patients, dT1/2 and early satiety, body mass index were related (P<0.05);GT1/2 was negative correlated with age (P<0.05). Taking gastric emptying and symptoms for logistic regression analysis, the only relationship was between delayed distal gastric emptying and early satiety (P<0.05). There were negative correlations between proximal gastric area at 20, 40 min, total gastric area at 40 min and epigastric burning (P<0.05). Distal gastric area at 20, 40 min and early satiety were negative correlated (P<0.05). Conclusion Abnormal gastric emptying existed in some patients with FD, delayed distal gastric emptying and early satiety were related.
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