Cu(Otf)2 Catalyzed Synthesis of Bis(5-methyl-2-furyl)methanes by Condensation of 2-Methylfuran with Carbonyl Compounds under Solvent Free Conditions

摘要

A facile and efficient one-pot three-component synthesis of bis(5-methyl-2-furyl)methanes has been achieved via the reaction of 2-methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones in presence of copper(H) triflate under solvent free conditions. The bis(5-methyl-2-furyl)methanes were obtained in 34％-72％yields and the catalyst was recycled up to four successive cycles without much loss in catalytic activity.