首页> 中文期刊> 《中国癌症研究:英文版》 >A CLINICAL STUDY ONINTRALUMINAL HYPERTHERMIA COMBINED WITH EXTERNAL IRRADIATION FOR ESOPHAGEAL CARCINOMA

A CLINICAL STUDY ONINTRALUMINAL HYPERTHERMIA COMBINED WITH EXTERNAL IRRADIATION FOR ESOPHAGEAL CARCINOMA

         

摘要

A randomized trial of intracavitary microwavehyperthermia combined with external irradiation (R+H)versus radiation (R) alone in the treatment of esophagcalcancer was performed form February 1986 to February1988. In the R group, radiation was given hy 8 MV X-ray with 2 Gy/fraction, 5 fractions per week with a totaldose of 60 Gy/6 weeka. In the R+H group, the radiationwas given as R group but with a total dose of 40 Gy/4weeks. lntracavitary 915 Mhz microwave hyperthermiawas given with a nominal temperature of 43.5℃ at themargin of the tumor surface, 45 minutes/session, 1-2sessions/week for 4-8 session. The 1-, 3-, and 5-yearsurvival rates in R+H group were 81.2% (48/59 cases),42.4% (25/59) and 23.7%, (14/59), while in the R group59.0% (39/66 cases), 24.2% (16/66) and 16.7% (11/66)respectively. The differences in 1-and 3-year survivalrates were statistically significant (P0.05) betwecn the 2groups. Using the thermal dose T90 analysis, after thecases with T9043℃ (insufficient thermal dose)

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