Obejective:Diastolic dysfunction (DD) identifies patients with increased cardiovascular risk. The aim of this study was to investigate the regional distribution of abnormal segmental relaxation in hypertensives with normal global diastolic func-tion. Methods:105 individuals were evaluated,consisting of 70 hypertensives and 35 middle-aged volunteers as control. None had DD. Segmental early and late diastolic Doppler-derived strain rates (SRs) were recorded from 18 segments in the longi-tudinal axis. Mean relaxation of the basal,mid,and apical regions was also calculated. Results:Volunteers had evidence of seg-mental DD that was mostly distributed at the basal parts of the heart ,in particular at the septal wall. Hypertensive patients had a lower mean relaxation at the basal,mid,and apical regions,with the basal parts appearing more compromised and with higher segmental DD compared with controls. Segmental DD in that group was more extensive towards the mid and even apical re-gions,with the septal and basal inferior walls being the most heavily affected areas. The lateral wall and apical regions were more resistant to diastolic abnormalities in both groups. Conclusions:Strain echocardiography has an incremental value over global indices of DD for early detection of diastolic abnormalities.%目的：探讨应变率成像在左室整体舒张功能正常高血压患者局部心肌功能评价中的应用，并分析其临床意义。方法：选择左室整体舒张功能正常高血压患者70例和健康志愿者35例（对照组），在长轴上记录各节段性18个节段舒张早、晚期应变率，计算各节段平均值。结果：对照组节段性舒张功能异常大部分分布在基底段（基底段舒张早期峰值应变率SRE、舒张晚期峰值应变率SRA及SRE/SRA值小于中间段及心尖段），特别是室间隔。高血压组平均松弛性较低，较对照组有较明显的节段性舒张功能异常，舒张功能异常最显著的区域为室间隔基底段、下壁基底段和前壁基底段。2组侧壁均是舒张功能异常表现最少的区域。结论：应变率成像可准确评价左室整体舒张功能正常高血压患者的局部心肌功能异常。
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