Objective To observe the efficacy and safety of argon plasma coagulation combined with drugs in treating acute nonvariceal upper gastrointestinal bleeding. Methods Twenty - seven patients with acute nonvariceal upper gastrointestinal bleeding received the treatment of argon plasma coagulation combined with drugs. Adverse reactions were observed. Results Among the 27 cases, secondary bleeding was observed in one with post bulbar duodenal ulcer bleeding on the second day after treatment and in another case with duodenal ulcer bleeding on the first day after treatment. Both cases underwent emergency en-doscopy and argon plasma coagulation therapy which stopped the bleeding successfully. No secondary bleeding was observed in the remaining cases. All patients recovered. No hemostatically invalid cases were noted, nor open operation or death were reported. Conclusion Argon plasma coagulation combined with drugs therapy is both safe and effective in treating acute nonvariceal upper gastrointestinal bleeding.%目的 观察氩离子凝固术联合药物治疗急性非静脉曲张性上消化道出血的有效性及安全性.方法 对在我院住院的27例上消化道特殊部位溃疡出血的患者行氩离子凝固术联合药物治疗,并观察其不良反应.结果 在治疗的27例患者中,1例十二指肠球后溃疡在术后第2天治疗过程中再次出血,1例十二指肠球部溃疡出血患者在术后第1天治疗过程中再次出血,均经紧急内镜检查发现出血灶后在视野清晰下予氩离子凝固术处理后未继续出血;其余上消化道出血患者均未再出血.27例患者均康复出院,未发生因止血无效或穿孔转外科手术或死亡的病例.结论 氩离子凝固术联合药物治疗急性非静脉曲张性上消化道出血安全、有效.
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