盆腔炎患者应用盐酸左氧氟沙星的临床疗效观察

摘要

目的：探讨盆腔炎患者应用盐酸左氧氟沙星的临床优势。方法：选取2014年3月-2015年3月笔者所在医院收治的160例盆腔炎患者为研究对象，按照随机数字表法将其均分为试验组和对照组，每组80例。试验组患者给予盐酸左氧氟沙星治疗，对照组患者给予氧氟沙星治疗。对比两组患者治疗结束后的临床疗效、治疗前后C-反应蛋白(C-reactive protein，CRP)、白细胞计数(white blood cell count，WBC)水平的变化情况、治疗期间不良反应发生情况以及随访6个月的复发情况。结果：试验组患者治疗总有效率98.75%显著高于对照组的90.00%，差异有统计学意义(P<0.05)；治疗后，两组患者CRP与WBC水平均明显低于同组治疗前，差异均有统计学意义(P<0.05)；治疗后，试验组患者CRP与WBC水平均明显低于对照组，差异均有统计学意义(P<0.05)；试验组患者治疗期间不良反应总发生率7.50%显著低于对照组的25.00%，差异有统计学意义(P<0.05)；试验组随访期间的复发率5.00%明显低于对照组的15.00%，差异有统计学意义(P<0.05)。结论：盐酸左氧氟沙星治疗盆腔炎较氧氟沙星疗效更佳，抗炎效果更明显，不良反应更少，复发率更低，可作为临床优选药物。%Objective:To explore the clinic advantages of Levofloxacin Hydrochlo on patients with pelvic inflammatory disease.Method:One hundred and sixty cases of patients with pelvic inflammatory disease admitted to our hospital from March 2014 to March 2015 were selected as the objects and randomly divided into the experiment group and the control group,the experiment group was treated by Levofloxacin Hydrochlo,while the control group was treated by Ofloxacin, the clinical effects,CRP,the levels of WBC,the adverse reactions and the recurrence rate were compared.Result:The total effective rate for the experiment group was 98.75%,higher than 90.00%of the control group,the difference was statistically significant(P<0.05).The CRP,the levels of WBC in the two groups after treatment were lower than before treatment,the differences were statistically significant(P<0.05).The CRP,levels of WBC in the experiment group after treatment were lower than those of the control group,the differences were statistically significant(P<0.05).The rate of adverse reactions of the experiment group were 7.50%,lower than 25.00%of the control group,the difference was statistically significant(P<0.05).The recurrence rate of the experiment group was 5.00%,lower than 15.00%of the control group,the difference was statistically significant(P<0.05).Conclusion:Levofloxacin Hydrochlo has better clinical effects on the patients with pelvic inflammatory disease,with more obvious anti-inflammatory effect,no adverse reactions,low recurrence rate,it can be used as a clinical preferred drug.