幽门螺杆菌感染与胆汁反流的临床关系

摘要

Objective:To explore the clinical relationship between infection of helicobacter pylori and bile reflux.Method:256 patients underwent gastroscopy in our hospital from January 2014 to June 2014 were selected,according to the results of gastroscopy,they were divided into A group and B group, the patients of A group with bile reflux,while the patients of B group without bile reflux.All patients underwent rapid urease test, and according to the judgement of the detection with Helicobacter pylori infection,positive rate of Helicobacter pylori infection in two groups were compared.Result:There were 28 cases in the A group and the positive rate of helicobacter pylori was 32.1%. However,there were 228 cases in the B group and the positive rate of helicobacter pylori was 67.1%, the difference was statistically significant(P<0.01).Conclusion:The refluent bile can inhibit or kill helicobacter pylori.%目的：探讨幽门螺杆菌感染与胆汁反流的临床关系。方法：选取2014年1-6月于笔者所在医院行胃镜检查的256例患者，根据胃镜检查结果，分为A组、B组，A组患者均存在胆汁反流，B组患者无胆汁反流。所有患者均行快速尿素酶试验检测，并根据其检测结果判定有无幽门螺杆菌感染，比较两组患者幽门螺杆菌感染的阳性率。结果：A组28例，幽门螺杆菌阳性率为32.1%，B组228例，幽门螺杆菌阳性率为67.1%，两组比较差异有统计学意义(P<0.01)。结论：反流的胆汁可能能够抑制或杀灭幽门螺杆菌。