糖尿病合并高血压患者有效降压药物的选择

摘要

Objective:To explore the selection of effective antihypertensive drugs in patients with diabetes mellitus complicated with hypertension.Methods:273 cases of diabetic patients with hypertension were selected.We analyzed the use of antihypertensive drugs and the choice of methods.Results:In this study,48 cases(17.6%) took amlodipine besylate;32 cases(11.7%) took nifedipine sustained release tablets;24 cases(8.8%) took felodipine sustained-release tablets;28 patients(10.26%) took candesartan cilexetil;22 cases(8.06% ) took valsartan;15 cases(5.49% ) took irbesartan;20 patients(7.33% ) took enalapril;15 cases(5.49% ) took benazepril;17 cases(6.23%) took captopril;15 cases(5.49%) took indapamide;10 cases(3.66%) took furosemide;27 cases(9.89%) took metoprolol sustained-release tablets.The control of blood pressure in 273 cases was good.After treatment,the patient's systolic blood pressure was (127.4±6.9)mmHg,and diastolic blood pressure was (74.4±7.9)mmHg.Conclusion:The incidence of diabetes mellitus complicated with hypertension was higher,and the difference of different antihypertensive drugs was larger.In the treatment,the patients should adhere to the principle of individuation,pay attention to the dynamic monitoring of blood glucose and blood pressure,timely adjust the treatment plan,improve the clinical treatment effect,and reduce the occurrence of vascular events.%目的：探讨糖尿病合并高血压患者有效降压药物的选择方法。方法：收治糖尿病合并高血压患者273例，分析降压药物的使用情况及选择方法。结果：本次研究中，48例(17.6%)服用苯磺酸氨氯地平，32例(11.70%)服用硝苯地平缓释片，24例(8.8%)服用非洛地平缓释片，28例(10.26%)服用坎地沙坦酯，22例(8.06%)服用缬沙坦，15例(5.49%)服用厄贝沙坦，20例(7.33%)服用依那普利，15例(5.49%)使用贝那普利，17例(6.23%)服用卡托普利，15例(5.49%)服用吲达帕胺，10例(3.66%)服用呋塞米，27例(9.89%)服用美托洛尔缓释片。273例血压控制情况良好，患者用药后收缩压(127.4±6.9)mmHg，舒张压(74.4±7.9)mmHg。结论：糖尿病合并高血压发病率较高，且应用不同降压药物差异较大，患者在治疗时应坚持个体化原则，注意动态监测血糖和血压，及时调整治疗方案，提高临床治疗效果，减少血管事件发生。