脊柱内固定术后感染分析与内置物保留治疗

摘要

Objective:To analyze the postoperative infection of patients with spinal internal fixation and to observe the clinical effect of internal retention therapy.Methods:35 cases of patients with postoperative infection treated with spinal internal fixation were as the observation group.35 cases of patients with non postoperative infection treated with spinal internal fixation were as the control group.The causes of infection and the clinical effect of internal retention therapy was analyzed.Results:Compared with the control group,the patients in the observation group was older,the operation time was significantly longer,and the amount of blood loss was significantly increased(P<0.05).The distribution of pathogens in 35 cases of patients with postoperative infection:16 cases with staphylococcus aureus (45.7%),10 cases with Klebsiella pneumoniae (28.6%),9 cases with Escherichia coli(25.7%). After treatment,the levels of C reactive protein,leucocyte and neutrophil in patients with infection were significantly lower than before treatment(P<0.05).Conclusion:The age,operation time and intraoperative blood loss were the common causes for postoperative infection.Internal retention therapy for postoperative infection after spinal internal fixation had good effect.%目的：分析脊柱内固定患者术后感染情况，观察内置物保留治疗的临床效果。方法：收治脊柱内固定术后感染患者35例作为观察组，选取行脊柱内固定术但未感染的患者35例作为对照组，分析引起感染的原因及内置物保留治疗的临床效果。结果：与对照组相比，观察组的年龄较大，手术时间明显较长，且术中出血量显著增加(P＜0.05)。35例术后感染患者的病原菌分布情况：金葡菌16例(45.7%)，克雷伯菌10例(28.6%)，大肠埃希菌9例(25.7%)。治疗后，感染患者的C反应蛋白、白细胞及中性粒细胞水平均较治疗前显著降低(P＜0.05)。结论：年龄、手术时间、术中出血量为引起患者发生术后感染的常见原因。内置物保留治疗脊柱内固定术后感染具有良好的效果。