Improved microwave-assisted catalyst-free synthesis of9-aryl-5,9-dihydropyrimido4,5-d1,2,4triazolo1,5-apyrimidine-6,8(4H,7H)-dione derivatives

摘要

Agreen regioselective synthesis of some new and known 9-aryl-5,9-dihydropyrimido[4,5-d][l,2,4]triazolo[1,5-a]pyrimidine-6,8(4H,7H)-diones has been described via the microwave-assisted one-pot reaction of 3-amino-lH-l,2,4-triazoles,aromatic aldehydes and barbituric acids under solvent- and catalyst-free conditions.This operationally simple procedure is less laborious and provides a better scope than previously reported procedures.