A new ureido-substituted amino acid from the tubers of Gymnadenia conopsea

摘要

A new ureido-substituted amino acid,conopsamide A(1),has been isolated from an ethanolic extract of the tubers of Gymnadenia conopsea.Its structure was elucidated by extensive spectroscopic analysis,and the absolute configuration was assigned by Marfey's method.The new compound was evaluated for in vitro assay for HDACl(Histone Deacetylase 1) inhibitory activity.