热毒宁注射液联合宣白承气汤治疗老年慢性阻塞性肺疾病急性加重期疗效评价

摘要

目的：探讨热毒宁注射液联合宣白承气汤治疗老年慢性阻塞性肺疾病急性加重期（AECOPD）的疗效及其对炎症指标的影响。方法选取老年AECOPD患者60例，随机分为观察组和对照组，各30例。对照组患者给予西医常规治疗，观察组患者在对照组基础上加用热毒宁注射液联合宣白承气汤，均治疗7 d。结果治疗后，观察组总有效率为90.00%，高于对照组的70.00%（ P0.05），二氧化碳分压( PaCO2)则显著下降、动脉血氧分压( PaO2)显著上升（ P 0. 05),but PaCO2 decreased significantly,PaO2 increased significantly( P < 0. 05),moreover tbe varied range in tbe observation group was more remarkable( P < 0. 05);tbe CRP and PCT levels in tbe two groups were significantly decreased,moreover tbe decrease in tbe observation group was more significant( P < 0. 05);no serious adverse reaction occurred during tbe treatment course in tbe two groups. Conclusion Reduning injection combined witb Xu-anbaicbengqi decoction in treating elderly patients witb AECOPD bas good clinical efficacy,can significantly improve symptoms,signs and blood gas analysis,reduce inflammatory response witb bigb safety,and is wortb of clinical promotion.