光照对静脉滴注过程中马来酸桂哌齐特注射液稳定性的影响

摘要

目的 考察马来酸桂哌齐特注射液与0.9%氯化钠注射液配伍的稳定性.方法 模拟临床用药,观察马来酸桂哌齐特注射液与0.9%氯化钠注射液配伍在室温自然光、遮光、光照条件下配伍液7 h内的外观,并采用紫外分光光度法测定马来酸桂哌齐特的含量.结果 配伍液中马来酸桂哌齐特的含量、pH及外观均无明显变化.结论 马来酸桂哌齐特注射液与0.9%氯化钠注射液配伍后遮光条件下7h内稳定.%Objective To investigate the stability of compatibility of Cinepazide Maleate Injection and 0. 9% Sodium Chloride Injection. Methods Simulating the clinical medication, the appearance of compatibility of Cinepazide Maleate Injection and 0. 9% Sodium Chlo-ride Injection was observed in 7 h under room temperature with natural light, shading and light conditions, and the content of cinepazide maleate was determined by UV spectrophotometry. Conclusion The content, pH and appearance of cinepazide maleate in the mixture solution showed no obvious change. Conclusion The compatibility of Cinepazide Maleate Injection and 0. 9% Sodium Chloride Injection is stable under the condition of shading within 7 h.