目的：探讨严重外伤性脾破裂切除加自体脾移植的临床疗效。方法选取我院2013年1月~2014年8月入院手术治疗的35例外伤性脾破裂患者做为研究对象。按照入院顺序随机分为治疗组17例与对照组18例，治疗组患者应用脾切除加脾移植术治疗，对照组患者仅应用脾切除无移植治疗。对比两组患者的脾功能恢复及血小板变化情况。结果治疗组患者的体液免疫与细胞免疫水平显著优于对照组患者，差异有统计学意义（P＜0.05）。治疗组患者手术后血小板增幅低于对照组，差异有统计学意义（P＜0.05）。治疗组患者的并发症发生率显著低于对照组患者，差异有统计学意义（P＜0.05）。结论通过严重外伤性脾破裂患者实施脾切除加自体脾移植治疗，脾功能恢复良好，血小板变化小，临床值得广泛推广应用。%Objective To investigate the clinical efficacy of resection and autologous transplantation in severe traumatic rupture of the spleen. Methods 35 hospitalized surgical treatment of patients with traumatic rupture in our hospital from January 2013 to August 2014 were selected as the object of study. According to the order of admission they were randomly divided into a treatment group in 17 cases and a control group in 18 cases, patients in the treatment group received spleen resection and spleen transplantation therapy, the control group only received transplant therapy without spleen transplantation. The function of splenic recovery and changes of platelet between the two groups were compared. Results The level of humoral immunity and cellular immunity in treatment group was significantly better than that in the control group,the difference was statistically significant (P<0.05). Platelet growth postoperative of patients in the treatment group was lower than that of the control group, the difference was statistically significant (P<0.05). The incidence of complications in the treatment group was significantly lower than that in the control group, the difference was statistically significant (P < 0.05). Conclusion Patients with severe traumatic rupture of the implementation of splenectomy and autologous spleen transplantation therapy, spleen function recovered well, small changes in platelet clinical worthy widely used.
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