不同治疗措施对早产儿坏死性小肠结肠炎发生影响的研究

摘要

Objective To explore the effects of different therapeutic interventions on necrotizing enterocolitis in preterm infants. Methods The clinical data of 450 cases of preterm infants were studied retrospectively, among whom 54 cases suffered with necrotizing enterocolitis (NEC). The effects of three kinds of intervening measures on necrotizing enterocolitis in preterm infants were observed. Results Preterm infants with NEC were experienced more PRBC transfusions and more weeks of antibiotic therapy for nosocomial infection, but mechanical ventilation time was not related with the development of NEC. Conclusion PRBC transfusions and nosocomial infection antimicrobial treatment may affect the incidence of NEC in preterm infants.%目的 探讨不同治疗干预措施对早产儿坏死性小肠结肠炎发生的影响.方法 回顾性研究450例早产儿的临床资料,其中,坏死性小肠结肠炎患儿54例,观察三种治疗干预措施对早产儿坏死性小肠结肠炎发生的影响.结果 患坏死性小肠结肠炎的早产儿输注浓缩红细胞较多,院内感染抗菌治疗时间较长,与机械通气时间无关.结论 浓缩红细胞输注、院内感染抗菌治疗可能影响早产儿坏死性小肠结肠炎的发生.