不同糖耐量个体外周血的白细胞计数与糖脂代谢指标的相关研究

摘要

Objective To investigate the correlation between peripheral blood leukocyte count and glycolipid metabolism indicators of individuals with different glucose tolerance. Methods Forty people with normal glucose tolerance (NGT), 40 people with injured glucose tolerance (IGT) and 40 people with diabetes mellitus (DM) were selected. Height, weight, blood pressure, blood glucose and blood lipids were measured and then changes of leukocyte in different groups were compared and the correlation between peripheral blood leukocyte count and glycolipid metabolism indicators were analyzed. Results The leukocyte count of IGT group was significantly higher than that of NCI group, with statistical difference (P < 0.05); the leukocyte count of DM group was significantly higher than that of IGT group, with statistical difference (P < 0.05). The leukocyte count and 2-hours postprandial blood glucose (2 h PG) and glycosylaied hemoglobin (HbAk) were positively correlated (r - 0.332, P < 0.01 and r=0.250, P < 0.05). Conclusion Leukocyte count and glycolipid metabolism status are closely correlated.%目的 探讨不同糖耐量个体外周血白细胞计数与糖脂代谢指标的相关性.方法 选取糖耐最正常(NGT)者、糖耐量受损(IGT)者、糖尿病(DM)患者各40例,测量身高、体重、血压、血常规、血糖、血脂,比较各组白细胞计数的变化,并分析白细胞计数与糖脂代谢指标的相关性.结果 IGT组白细胞计数较NGT组明显升高,差异有统计学差异(P<0.05),DM组白细胞计数较IGT组明显升高,差异有统计学差异(P<0.05);白细胞计数与餐后2 h 血糖(2 h PG)和糖化血红蛋白(HbAlc)呈正相关(r=0.332,P<0.01和r=0.250,P<0.05).结论 白细胞计数与糖脂代谢状态密切相关.