正交试验优选暖脐膏醇提工艺

摘要

Objective To optimize the extraction process of Nuanai Slicking Plaster. Methods The extraction process of Nuanqi Sticking Plaster was optimized by using orthogonal test with the concentration and amount of alcohol, and the extraction time and extraction times was used as factors, with the content of ferulic acid as index. Results The best extraction process of Nuanqi Sticking Plaster was as follows: nine times volume of/5% alcohol were used to extract the materials the first time for 90 minutes and six times volume of 75% alcohol for the second time for 60 minutes. Conclusion The above extraction procedure is feasible and served as a theoretic reference for the industrialized production.%目的 优选暖脐膏处方最佳的提取工艺.方法 采用L9(34)正交试验,以复方中主要药材当归中阿魏酸的含量为考察指标,以乙醇的浓度、用量、提取时间以及提取次数为考察因素,得出最佳的提取工艺.结果 最终确定的最佳提取工艺为第1 次加9 倍量75%乙醇,回流提取90 min,第2 次加6 倍量75%乙醇,回流提取60 min.结论 该工艺简单方便,稳定性好,可作为工业化生产的参考路线.