327例儿童细菌性肺炎病原体分布及耐药性分析

摘要

Objective To study the pathogens distribution and drug resistance of bacterial pneumonia in children.Methods 327 cases of clinically diagnosed children with bacterial pneumonia cases sputum culture and drug sensitivity analysis results in the People's Hospital of Xiangtan County from January 2010 to January 2012 were analyzed and summarized the distribution and drug resistance of pathogens.Results In 327 patients with bacterial pneumonia strains distribution: G- coli infection in 198 cases, accounted for 60.6%, Klebsiella pneumoniae (17.4%), Pseudomonas aerugi-nosa (15.0%), Bauman Acinetobacter (9.8%), Escherichia coli (8.0%) were more common; G+ cocci infection in 129 cases, accounted for 39.4%, Staphylococcus Staphylococcus aureus (11.6%), Streptococcus pneumoniae (9.8%) were relatively common in the region, imipenem was sensitive to G- coli; vancomycin, levofloxacin are more sensitive to G+ aureus, the other all existed the different degree of resistance phenomenon.Conclusion Antibacterial drug use in clinical should refer to drug sensitivity test, reasonable use of antibiotics can reduce the resistance of bacteria to produce.%目的 研究儿童细菌性肺炎感染病原体的分布情况及耐药现象.方法 分析2010年1月～2012年1月湖南省湘潭县人民医院327例临床确诊为细菌性肺炎的儿童病例痰培养及药敏分析结果,总结感染病原体的分布及耐药情况.结果 327例细菌性肺炎主要菌种分布:G-杆菌感染198例,占60.6％,其中,肺炎克雷伯菌(17.4％)、铜绿假单胞菌(15.0％)、鲍曼不动杆菌(9.8％)、大肠埃希菌(8.0％)比较常见；G+球菌感染129例,占39.4％,其中,金黄色葡萄球菌(11.6％)、肺炎链球菌(9.8％)比较常见；在本地区亚胺培南对主要G-杆菌比较敏感；万古霉素、左氧氟沙星对主要G+球菌比较敏感,其他均存在不同程度的耐药现象.结论 临床应以药敏实验指导用药,合理使用抗生素,尽量减少耐药菌群的产生.