目的 探讨稳定期慢性阻塞性肺疾病(COPD)患者呼吸症状水平与下肢功能能力的相关性.方法 于2016年9月～2017年1月采用自制的一般情况调查表、慢性阻塞性肺疾病评估测试问卷(CAT)、英国医学研究会呼吸困难量表(MMRC)以及6 min步行测试(6MWT)对苏州大学附属第一医院门诊就诊的109例稳定期COPD患者进行调查研究.测量稳定期COPD患者的MMRC、CAT得分以及6 min步行距离(6MWD),并分析变量间的相关性.结果 稳定期COPD患者6MWD平均为(440.97±91.55)m,单因素分析表明下肢功能能力受患者年龄、急性发作次数、病程以及病情严重程度的影响(P＜0.01).下肢功能能力与MMRC、CAT总分、爬坡或上一层楼梯的感觉、家务活动以及离家外出信心程度得分呈负相关(r＜0,P＜ 0.01).分层回归分析表明,呼吸症状能独立影响下肢功能能力水平总体变异的10％.结论 加强稳定期COPD患者呼吸症状的管理,减少患者发病次数,有助于促进其下肢功能能力的恢复.%Objective To explore the relationship between respiratory symptoms level and lower extremity functional performance for patients with stable chronic obstructive pulmonary disease (COPD).Methods 109 patients of stable COPD outpatients in the First Affiliated Hospital of Soochow University from September 2016 to January 2017 were investigated by homemade general information questionnaire,chronic obstructive pulmonary disease assessment test (CAT),modified medical research council dyspnea scale (MMRC) and six-minute walking test (6MWT).The MMRC,CAT and six-minute walking distance (6MWD),and the correlations of variables were analyzed.Results 6MWD of patients with stable COPD was (440.97±91.55)m,and univariate analysis showed that the lower extremity functional performance was affected by age,acute attack times,course of disease and severity of disease (P ＜ 0.01).The lower extremity functional performance was negatively correlated with the MMRC,the total scores of CAT,feeling of climbing or climbing up a layer of stairs,household activities and confidence level away from home (r ＜ 0,P ＜ 0.01).Hierarchical regression analysis showed that the respiratory symptoms level could influence the lower extremity functional performance of the total variation 10％.Conclusion Strengthen the management of respiratory symptoms in patients with stable COPD and reduce attack times of patients,which can help to improve lower extremity functional performance.
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