右美托咪定清醒镇静在光棒辅助困难气道插管中的临床研究

摘要

Objective: To observe the feasibility of dexmedetomidine sedation application in light of the difficult airway intubation assisted. Methods: Selecting pseudo operation under general anesthesia, is expected to 60 cases of difficult airway patients, randomly divided into dexmedetomidine combined bar adjuvant therapy group(group A, n=20) and dexmedetomidine treatment group(group B, n=20), the general status of the two groups were observed and recorded the intubation time, intubation times and success rate, of the patients, and postoperative complications. Results:The results of dexmedetomidine combined with light auxiliary treatment group first intubation success rate is higher than the single use of dexmedetomidine treatment group, no significant difference;the intubation time than group B(t=63.18, P<0.05), in A group before and after intubation, HR MAP had no obvious change before and after MAP, B group, HR intubation, there was statistically significant difference. A group complications of lower than B group. Conclusion:Dexmedetomidine sedation application can improve the success rate of intubation in difficult airway intubation in light assisted, little side effects on patients, and reduce its complications.%目的：观察右美托咪定清醒镇静在光棒辅助困难气道插管中应用的可行性。方法：选择60例拟在全麻下手术，预计为困难气道患者，随机分为观察组和对照组，每组30例。观察组采用右美托咪定联合光棒辅助治疗，对照组采用单纯右美托咪定治疗，记录分析两组的插管时间、插管次数及成功率、患者的一般状况及术后并发症情况。结果：观察组首次插管成功率高于对照组；其插管时间优于对照组，差异具有统计学差异(t=63.18，P＜0.05)。观察组插管前后平均动脉压(MAP)、心率(HR)无明显变化，对照组的MAP、HR插管前后具有显著差异。观察组术后的并发症发生较对照组低，具有显著差异。结论：右美托咪定清醒镇静在光棒辅助困难气道插管中应用可提高插管成功率，对患者影响小，并可减少相应并发症的发生。