骨质疏松症患者危险因素分析及双能X射线骨密度仪检测扫描身体脂肪量增加与骨质丢失相关性分析

摘要

目的:探讨骨质疏松症患者危险因素,并应用双能X射线骨密度仪检测扫描骨质疏松症患者身体脂肪量增加与骨质丢失相关性.方法:选取医院收治的700例骨质疏松症患者,给予所有患者至少2次双能X射线检测仪检测体脂含量和骨密度情况,分析骨质疏松症患者骨折史及骨折危险因素,不同身体质量指数(BMI)患者身体脂肪量变化与骨密度指数T值变化情况,以及骨质疏松症患者脂肪量与骨密度T值相关性.结果:线性回归分析结果显示骨密度指数T值变化、骨盆骨折史、股骨骨折史以及炎症疾病史是骨质疏松症患者的危险因素;不同BMI组患者体脂含量变化数据比较,其差异无统计学意义(F=0.786,P>0.05),不同BMI患者骨密度指数T值变化数据比较,其差异无统计学意义(F=0.963,P>0.05);Logistics回归分析结果显示,骨质疏松症患者脂肪量增加与骨密度指数T值呈显著正相关(r=0.563,P<0.05).结论:双能X射线骨密度仪检测扫描分析能够准确反映骨质疏松症患者的体脂含量,骨质疏松症患者适当增加体脂含量,有利于增加骨密度,减少骨折风险.%Objective: To investigate the risk factors of patients with osteoporosis, and to apply bone mineral densimeter of Dual energy X-ray to scan increasing of body fat and losing of sclerotin of these patients and analyze their correlation. Methods: 700 patients with osteoporosis received scans by using bone mineral densimeter of Dual energy X-ray at least 2 times to detect the content of body fat and situation of bone mineral density. The fracture history and risk factors of fracture of patients with osteoporosis were analyzed, and the change of body fat and change of T index of patients with different BMI were analyzed. Besides, the correlation between body fat and T value of patients with osteoporosis also was analyzed and researched. Results: The linear regression analysis indicated that the risk factors of patients with osteoporosis included the change of T value, fracture history of pelvis, fracture history of femur and diseases history of inflammation. The differences of the changes of body fat among different BMI groups were no significant (F=0.786, P>0.05), and the differences of T value among different BMI groups also were no significant (F=0.963, P>0.05). The results of Logistics regression analysis indicated that there was a significant positive correlation between the increasing of body fat and T value in patients with osteoporosis (r=0.563, P<0.05). Conclusion: The bone mineral densimeter of Dual-energy X-ray can accurately reflect the content of body fat of osteoporosis patients. And the appropriate increasing of body fat of them is benefit for the increasing of bone mineral density and reducing of the risk of fracture.