富血小板血浆修复骨缺损的机制研究进展

摘要

富血小板血浆(platelet-rich plasma,PRP)是含有高浓度血小板的血浆,其中含丰富的生长因子,广泛应用于口腔颌面外科、骨科,用于骨组织、软骨组织和软组织的修复,其中生长因子对骨修复的多个阶段和多个方面都起作用,以血小板衍化生长因子(PDGF)和转化生长因子-β(TGF-β)的作用最为显著,机制研究也较为透彻.%Platelet-rich plasma (PRP) is a kind of plasma with high concentration of platelet, which includes a lot of growth factors. It was widely used in oral and maxillofacial surgery and orthopedics,for the repairing of bone,cartilage and soft tissues. The growth factors .especially PDGF and TGF-(3,plays an important role in different stages and aspects.