目的：研究贵阳城区40岁以上非超重社区居民代谢综合征（MS）发病情况。方法通过非超重MS发病者基线与随访终点比较、非超重发病者与非超重未发病者比较，经统计学分析，研究非超重MS发病者的发病情况及相关危险因子的作用。结果经过3年的随访，女性MS总发病率高于男性，非超重者MS发病率占总发病率的比例分别为男性25.11%、女性59.73%；受试者工作特征曲线分析相关危险因子与MS发病作用的结果显示男性腰围身高比的曲线下面积（AUC）值最高（0.909，95%CI：0.881，0.937），Cutoff值为0.52；女性三酰甘油（TG）的AUC值最高（0.807，95%CI：0.784，0.830），Cutoff值为1.70 mmol/L。结论贵阳城区40岁以上社区居民非超重者的MS发病情况值得重视，特别是女性非超重者发病率较高。在男性非超重发病者中腰围身高比有着较好的MS发病预测作用，而在女性则是TG水平。%Objective To study the incidence of metabolic syndrome (MS) in non-overweight residents over 40 years in Guiyang urban. Methods By comparing the baseline and follow-up endpoint of non-overweight MS patients, non-overweight MS patients and non-overweight non-MS patients, the risk factors of MS were researched. Results After 3-year follow-up, the overall incidence of the female MS patients was higher than that of the male patients, the proportion of the incidence of non-overweight MS in the total incidence was 25.11% in male and 59.73%in female. The AUC of the waist height ratio was the highest [0.909 (95% CI: 0.881, 0.937)] in male with the cutoff value of 0.52. However the AUC of TG was the highest [0.807 (95%CI:0.784, 0.830)] in female with the cutoff value of 1.70 mmol/l in the ROC curve analysis of risk factors associated with MS. Conclusions MS incidence of non-overweight Guiyang residents over 40 years deserves more attention, in particular the MS incidence of non-overweight female is high. Waist-height ratio is a better predictive factor of MS in non-overweight male, while in female it is TG level.
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