Objective To discuss the clinical effect of the application of endometrial biopsy in the diagnosis of abnormal u-terine bleeding. Methods 120 cases of patients with abnormal uterine bleeding treated in the department of gynaecology of our hospital from March 2013 to March 2015 were selected as the research object and all patients received endometrial biopsy, the diagnostic effect was discussed. Results The 120 cases of patients after endometrial biopsy showed that 19.2%were with uterine organic disease, among them, 21.7%were with abortion, 17.4%were with chronic endometritis, 8.7%were with uterine body adenocarcinoma, 52.2% were with endometrial polyp; and 40.8% were with endometria functional change caused by hormonal imbalance, among them, 59.2% were with hyperplasia, 10.2% were with poor endometrial secretion, 14.3%were with complex hyperplasia, 6.1%were with out-of-sync endometrial secretion response, 10.2%were with irregu-lar shedding endometrial secretion; 40.0% were with endometrium of each phase in normal menstrual cycle, among them, 31.3% were with secretory phase endometria, 56.3% were with estrin phase endometria, 12.5% were with menstrual phase endometria. Conclusion The application of endometrial biopsy in abnormal uterine bleeding has an obvious clinical diag-nostic effect, and it can obviously improve the diagnostic rate of endometrial lesions and is convenient to timely diagnosis and treatment with high clinical value, which is worth promotion.%目的：探讨在诊断异常子宫出血患者中应用子宫内膜活检的临床效果。方法随机选取该院妇科2013年3月-2015年3月收治的异常子宫出血患者120例作为研究对象,所有患者均行子宫内膜活检,探讨其诊断效果。结果120例患者接受子宫内膜活检后发现19.2%为子宫器质性疾病,其中21.7%流产,17.4%为慢性子宫内膜炎,8.7%为宫体腺癌,52.2%为子宫内膜息肉；40.8%为激素水平失调后导致的子宫内膜功能性改变,其中59.2%为子宫内膜单纯性增生,10.2%为子宫内膜分泌欠佳,14.3%为复杂性增生,6.1%为子宫内膜分泌反应不同步,10.2%为子宫内膜呈不规则脱卸样改变。40.0%为正常月经周期各期子宫内膜,其中31.3%为分泌期内膜,56.3%为增生期,12.5%为月经期。结论在异常子宫出血中应用子宫内膜活检诊断临床效果明显,可显著提升子宫内膜病变诊断率,便于及时诊治,临床价值高,值得推广。
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